Endocrine Abstracts

A 41-year-old female was diagnosed with generalised seizures in 1984 and her EEG showed excess slow wave activity in the temporal region. She was commenced on carbamazepine. In 2005 she was diagnosed to have a bipolar affective disorder for which olanzapine was added.She was found to be hypocalcaemic with corrected calcium of 2.08 mmol/l in 2005 after sustaining a right undisplaced distal radial fracture following a seizure. She was empirically commenced...

Background: Glucocorticoids play a key role in determining body fat distribution. Excess circulating glucocorticoids lead to intrahepatic fat accumulation. Obesity is associated with enhanced glucocorticoid production but this is offset by enhanced degradation such that circulating steroid concentrations are normal. However, tissue-specific pathways may lead to different degrees of cortisol exposure in different organs. Local steroid exposure in the liver is determined by the ...

Aim: To assess the outcome of thyroid surgery in a District General Hospital.Methods: Retrospective study of thyroid surgery done over a 3-year period(1999-2002). Indications for surgery, pre and postoperative thyroid status, extent of surgery, post operative complications and post operative histology were evaluated.Results: 124 patients underwent surgery for thyroid disease. 90 % were female and 10 % male, median age of 52 years (...